Kurdistan University of Medical Sciences Journal of Advances in Environmental Health Research 2676-3478 14 1 2026 02 01 How Versatile Are Advanced Oxidation Processes (AOPs) in Addressing Different Wastewater Pollutants in Full-Scale Applications? 1 17 242852 10.34172/jaehr.1422 EN Meghdad Pirsaheb Department of Environmental Health Engineering, Faculty of Health, Kermanshah University of Medical Sciences, Kermanshah, Iran 0000-0001-9189-772X Hooshyar Hossini Department of Environmental Health Engineering, Faculty of Health, Kermanshah University of Medical Sciences, Kermanshah, Iran 0000-0002-4049-9235 Tooraj Massahi Research Center for Environmental Determinants of Health (RCEDH), Kermanshah University of Medical Sciences, Kermanshah, Iran Students Research Committee, Kermanshah University of Medical Sciences, Kermanshah, Iran 0000-0002-3602-2151 Monireh Nouri Research Center for Environmental Determinants of Health (RCEDH), Kermanshah University of Medical Sciences, Kermanshah, Iran Students Research Committee, Kermanshah University of Medical Sciences, Kermanshah, Iran 0000-0001-6927-6054 Journal Article 2025 02 16 This study presents a comprehensive review of the utilization of advanced oxidation processes (AOPs) for full-scale wastewater treatment. The review included 28 studies conducted in 11 countries across Europe, Asia, and the Americas. The studies investigated various wastewater types municipal, industrial (e.g., textile), and biological- which contain a broad range of pollutants such as micropollutants, antibiotic-resistant bacteria, resistance genes, pharmaceuticals, pesticides, trace pollutants, endocrine disrupting chemicals (EDCs), organic pollutants, and refractory matter. The reviewed studies employed different AOPs, including UV/H₂O₂, UV/persulfate, UV/chlorine, ozonation, Fenton, electro-Fenton, photo-Fenton, and electrochemical oxidation. The pros and cons of each AOP are summarized, and their performance in wastewater treatment is compared. The review emphasizes the versatility of AOPs in dealing with different environmental concerns and their capability for widespread use in wastewater treatment plants. Moreover, the current study tackles the challenges as to scaling up AOPs, and focuses on the need for further research to improve their efficiency and cost-effectiveness. https://jaehr.muk.ac.ir/article_242852_ba8253048b337335f6366405897a9b0b.pdf